RIPK1-IN-12
Product Specifications
CAS Number
2173556-92-6
Target
Necroptosis, RIP kinase
Related Pathways
NF-κB, Apoptosis
Bioactivity
RIPK1-IN-12 is a potent inhibitor of RIPK1, exhibiting an inhibitory effect on necroptosis in human and mouse cells with EC50 values of 1.6 and 2.9 nM, respectively.
Smiles
N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(C3)C=4C=C(NC(OC5CCCCC5)=O)C(C)=NC4
Molecular Formula
C24H26N4O3S
Molecular Weight
450.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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