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RIPK1-IN-12

Product Specifications

CAS Number

2173556-92-6

Target

Necroptosis|||RIP kinase

Related Pathways

NF-?B|||Apoptosis

Bioactivity

RIPK1-IN-12 is a potent inhibitor of RIPK1, exhibiting an inhibitory effect on necroptosis in human and mouse cells with EC50 values of 1.6 and 2.9 nM, respectively.

Smiles

N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(C3)C=4C=C(NC(OC5CCCCC5)=O)C(C)=NC4

Molecular Formula

C24H26N4O3S

Molecular Weight

450.55

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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