OPC-14523 hydrochloride
Product Specifications
CAS Number
145969-31-9
Target
5-HT Receptor, Sigma receptor
Related Pathways
GPCR/G Protein, Neuroscience
Purity
0.997
Bioactivity
OPC-14523 hydrochloride is an orally active sigma and 5-HT1A receptor agonist with antidepressant-like activity, showing high affinity for the sigma receptor σ1/2 (IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM) .
Smiles
Cl.COc1cccc2N(CCCN3CCN(CC3)c3cccc(Cl)c3)C(=O)CCc12
Molecular Formula
C23H29Cl2N3O2
Molecular Weight
450.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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