Tipifarnib
Product Specifications
CAS Number
192185-72-1
Target
Transferase
Related Pathways
Metabolism
Purity
0.9922
Bioactivity
Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.
Smiles
Cn1cncc1[C@@](N)(c1ccc(Cl)cc1)c1ccc2n(C)c(=O)cc(-c3cccc(Cl)c3)c2c1
Molecular Formula
C27H22Cl2N4O
Molecular Weight
489.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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