RTI-7470-44
Product Specifications
CAS Number
825658-63-7
Target
Others
Related Pathways
Others
Bioactivity
RTI-7470-44 is a potent and selective human trace amine-associated receptor 1 (hTAAR1) antagonist (IC50: 8.4 nM) that crosses the blood-brain barrier. RTI-7470-44 increases the spontaneous firing rate of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain in mice. RTI-7470-44 can be used to study schizophrenia, drug addiction and Parkinson's disease (PD) .
Smiles
FC(F)(F)c1cc(nc(SCC(=O)Nc2ncccn2)c1C#N)-c1ccc(Cl)cc1
Molecular Formula
C19H11ClF3N5OS
Molecular Weight
449.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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