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(R) -MLT-985

Product Specifications

CAS Number

1832577-07-7

Target

MALT|||Others

Related Pathways

Others|||Immunology/Inflammation

Bioactivity

(R) -MLT-985 (compound 11) is a potent MALT1 protease inhibitor (IC50: 3 nM) and has an IC50 value of 20 nM for MALT1-dependent IL-2 in Jurkat cells. Additionally, (R) -MLT-985 inhibits the growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells.

Smiles

[C@@H](OC)(C)C=1N2C(N=CC1NC(NC=3C=C(Cl)C(=NC3)N4N=CC=N4)=O)=CC(Cl)=N2

Molecular Formula

C17H15Cl2N9O2

Molecular Weight

448.27

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/2140ECCE-7FCD-4EEC-A3B9-EC3410E8DF6A/T62680

Available Sizes

Curated Selection

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