CDK2-IN-12
Product Specifications
CAS Number
2410402-88-7
Target
Carbonic Anhydrase, Others, CDK
Related Pathways
Metabolism, Others, Cell Cycle/Checkpoint
Bioactivity
CDK2-IN-12 (compound 10b) is a potent inhibitor of CDK2 (IC50: 11.6 μM) and exhibits inhibition of hCA subtypes I, II, IX, and XII with KI values of 3534, 638.4, 44.3, and 48.8 nM, respectively. Additionally, CDK2-IN-12 shows anti-cancer effects.
Smiles
N(=N/C1=CC=C(S(N)(=O)=O)C=C1)\C2=C3N(C(N)=C(C#N)C(=N3)C4=CC=C(C)C=C4)N=C2N
Molecular Formula
C20H17N9O2S
Molecular Weight
447.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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