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HDAC-IN-34

Product Specifications

Target

MDM-2/p53|||Others|||Apoptosis|||HDAC

Related Pathways

Chromatin/Epigenetic|||Others|||Apoptosis|||DNA Damage/DNA Repair

Bioactivity

HDAC-IN-34 (compound 27) is a potent inhibitor of HDAC, targeting HDAC1 (IC50: 0.022 ?M) and HDAC6 (IC50: 0.45 ?M) . It can bind to DNA and induce DNA damage, exhibiting a significant anti-proliferative effect on HCT-116 cells (IC50: 1.41 ?M) .

Molecular Formula

C24H26N6O3

Molecular Weight

446.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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