FGFR3-IN-5
Product Specifications
UNSPSC Description
FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1].
Target Antigen
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fgfr3-in-5.html
Solubility
DMSO : 100 mg/mL (ultrasonic;warming;heat to 160°C)
Smiles
N#CC1=C2C(OC)=CC(C3=CN(C4CCN(CC4)C(C5(CN(C5)C(C=C)=O)F)=O)N=C3)=CN2N=C1
Molecular Weight
477.49
References & Citations
[1]James FB, et, al. Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases. WO2020131627.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148779/FGFR3-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148779/FGFR3-IN-5-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2446664-72-6
Available Sizes
Curated Selection
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