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Dizocilpine

Product Specifications

CAS Number

77086-21-6

Target

NMDAR, iGluR

Related Pathways

Membrane transporter/Ion channel, Neuroscience

Purity

0.9997

Bioactivity

Dizocilpine (MK-801) is a selective non-competitive NMDA receptor antagonist with a Kd of 37.2 nM that exhibits anticonvulsant effects. It acts by binding to a site within the NMDA-associated ion channel, blocking the flow of Ca2+, and is commonly used to establish schizophrenia models.

Smiles

C[C@]12C=3C([C@](N1)(CC=4C2=CC=CC4)[H])=CC=CC3

Molecular Formula

C16H15N

Molecular Weight

221.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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