Dizocilpine
Product Specifications
CAS Number
77086-21-6
Target
NMDAR|||iGluR
Related Pathways
Membrane transporter/Ion channel|||Neuroscience
Purity
0.9997
Bioactivity
Dizocilpine (MK-801) is a selective non-competitive NMDA receptor antagonist with a Kd of 37.2 nM that exhibits anticonvulsant effects. It acts by binding to a site within the NMDA-associated ion channel, blocking the flow of Ca²?, and is commonly used to establish schizophrenia models.
Smiles
C[C@]12C=3C([C@](N1)(CC=4C2=CC=CC4)[H])=CC=CC3
Molecular Formula
C16H15N
Molecular Weight
221.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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