What is the catalog number for JAK-IN-23?

The catalog number for JAK-IN-23 is T62556.

What sizes are available for JAK-IN-23?

JAK-IN-23 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does JAK-IN-23 come in?

JAK-IN-23 is available in 3 different pack sizes.

Is JAK-IN-23 in stock?

JAK-IN-23 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures JAK-IN-23?

JAK-IN-23 is manufactured by Molfinity.

What is the estimated delivery time for JAK-IN-23?

Estimated delivery time for JAK-IN-23 is approximately 10 business day(s), depending on your location.

JAK-IN-23

Product Specifications

Target

Others, STING, NF-κB, STAT, JAK

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Immunology/Inflammation, JAK/STAT signaling, NF-κB, Others, Chromatin/Epigenetic, Stem Cells

Bioactivity

JAK-IN-23 is an orally active dual JAK/STAT and NF-κB inhibitor that inhibits JAK1 (IC50: 8.9 nM), JAK2 (IC50: 15 nM), and JAK3 (IC50: 46.2 nM) . It exhibits strong anti-inflammatory effects and can reduce the release of various pro-inflammatory factors. JAK-IN-23 can be used to study inflammatory bowel disease (IBD) .