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PPARγ phosphorylation inhibitor 1

Product Specifications

CAS Number

2882975-84-8

Target

PPAR

Related Pathways

Metabolism, DNA Damage/DNA Repair

Purity

0.9986

Bioactivity

PPARγ phosphorylation inhibitor 1 (Compound 10) is an effective PPARγ agonist (IC50=24 nM) that inhibits CDK5-mediated PPARγ Ser273 phosphorylation (IC50=160 nM) and exhibits antidiabetic activity.

Smiles

O=C(O)C1=NN(C(=O)C=2C=C(OC=3C=CC=CC3)C=CC12)CC4=CC=C(Cl)C(Cl)=C4

Molecular Formula

C22H14Cl2N2O4

Molecular Weight

441.26

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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