HDAC-IN-43
Product Specifications
CAS Number
1809163-24-3
Target
Others, PI3K, mTOR, HDAC
Related Pathways
PI3K/Akt/mTOR signaling, Others, Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
HDAC-IN-43 is a potent HDAC 1/3/6 inhibitor with IC50 values of 82 nM for HDAC 1, 45 nM for HDAC 3, and 24 nM for HDAC 6, and a weak PI3K/mTOR inhibitor with IC50 values of 3.6 μM for PI3K and 3.7 μM for mTOR, exhibiting a broad-spectrum anti-proliferative effect.
Smiles
C(C)(C)N1C=2C(=C(N=C(N2)N3CCOCC3)C4=CC(OCCCC(NO)=O)=CC=C4)N=C1
Molecular Formula
C22H28N6O4
Molecular Weight
440.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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