What is the catalog number for Ipatasertib?

The catalog number for Ipatasertib is T6252.

What sizes are available for Ipatasertib?

Ipatasertib is available in the following size(s): 2 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Ipatasertib come in?

Ipatasertib is available in 7 different pack sizes.

Is Ipatasertib in stock?

Ipatasertib is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ipatasertib?

Ipatasertib is manufactured by Molfinity.

What is the estimated delivery time for Ipatasertib?

Estimated delivery time for Ipatasertib is approximately 10 business day(s), depending on your location.

Ipatasertib

Product Specifications

CAS Number

1001264-89-6

Target

Apoptosis, Akt

Related Pathways

PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis

Purity

0.9979

Bioactivity

Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that inhibits Akt1 (IC50:5 nM), Akt2 (IC50:18 nM), and Akt3 (IC50:8 nM) . Ipatasertib (GDC-0068) can lead to p53-independent PUMA activation by inhibiting Akt, thereby activating FoxO3a and NF-κB simultaneously, directly binding to the PUMA promoter, upregulating PUMA transcription and Bax-mediated intrinsic mitochondrial apoptosis.