What is the catalog number for HDAC-IN-46?

The catalog number for HDAC-IN-46 is T62514.

What sizes are available for HDAC-IN-46?

HDAC-IN-46 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does HDAC-IN-46 come in?

HDAC-IN-46 is available in 3 different pack sizes.

Is HDAC-IN-46 in stock?

HDAC-IN-46 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HDAC-IN-46?

HDAC-IN-46 is manufactured by Molfinity.

What is the estimated delivery time for HDAC-IN-46?

Estimated delivery time for HDAC-IN-46 is approximately 10 business day(s), depending on your location.

HDAC-IN-46

Product Specifications

CAS Number

2562386-85-8

Target

Apoptosis, Others, HDAC

Related Pathways

Chromatin/Epigenetic, Apoptosis, Others, DNA Damage/DNA Repair

Bioactivity

HDAC-IN-46 (compound 12c) is a potent inhibitor of HDAC, targeting HDAC1 (IC50: 0.21 μM) and HDAC6 (IC50: 0.021 μM) . It upregulates p-p38, downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells, blocks the cell cycle in the G2 phase, and induces apoptosis, making it useful for triple negative breast cancer (TNBC) studies.