EGFR/BRAFV600E-IN-1
Product Specifications
CAS Number
2492429-45-3
Target
Others, Apoptosis, EGFR, Raf
Related Pathways
Others, Apoptosis, MAPK, Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Bioactivity
EGFR/BRAFV600E-IN-1 (Compound 23) is a potent dual inhibitor of EGFR (IC50: 0.08 μM) and BRAFV600E (IC50: 0.15 μM), exhibiting anti-proliferative effects on A-549 (IC50: 1.2 μM), MCF-7 (IC50: 0.79 μM), Panc-1 (IC50: 1.3 μM), and HT-29 (IC50: 1.23 μM) .
Smiles
O=C1N2C(=C(C)C=3C2=CC=C(Cl)C3)C(=O)N(CCC4=CC=C(C=C4)N5CCOCC5)C1
Molecular Formula
C24H24ClN3O3
Molecular Weight
437.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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