Avagacestat
Product Specifications
CAS Number
1146699-66-2
Target
Gamma-secretase
Related Pathways
Neuroscience|||Proteases/Proteasome|||Stem Cells
Purity
0.9977
Bioactivity
Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable ?-secretase inhibitor of A?40 and A?42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
Smiles
NC(=O)[C@@H](CCC(F)(F)F)N(Cc1ccc(cc1F)-c1ncon1)S(=O)(=O)c1ccc(Cl)cc1
Molecular Formula
C20H17ClF4N4O4S
Molecular Weight
520.89
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal Perilipin-3/TIP47 Antibody [CoraFluor 1]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
