INCB38579
Product Specifications
CAS Number
1246207-65-7
Target
Histamine Receptor|||Others
Related Pathways
Neuroscience|||Others|||Immunology/Inflammation|||GPCR/G Protein
Bioactivity
INCB38579 is a selective, orally active, histamine H4 receptor (HH4R) antagonist that crosses the blood-brain barrier and acts on hH4R (IC50: 4.8 nM), mH4R (IC50: 42 nM), and rH4R (IC50: 32 nM) . INCB38579 has anti-inflammatory and antipruritic effects.
Smiles
CN1CCN(CC1)c1cc(nc(N)n1)-c1ccc2CCN(Cc2c1)C(=O)CC1CCCC1
Molecular Formula
C25H34N6O
Molecular Weight
434.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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