EGFR-IN-56
Product Specifications
CAS Number
2477726-83-1
Target
EGFR|||Apoptosis|||Others
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling|||Apoptosis|||Others
Bioactivity
EGFR-IN-56 (Compound 13a) is a potent inhibitor of EGFR, targeting EGFRT790M (IC50: 541.7 nM) and EGFRT790M/L858R (IC50: 132.1 nM), blocking the G2/M phase of the cancer cell cycle and inducing apoptosis.
Smiles
O(C1=C2C(=NC(NC3=CC=C(OC)C=C3)=N1)CCSC2)C4=CC(NC(C=C)=O)=CC=C4
Molecular Formula
C23H22N4O3S
Molecular Weight
434.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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