KPH2f
Product Specifications
CAS Number
2760615-09-4
Target
OAT, Others, transporter
Related Pathways
Metabolism, Others, Membrane transporter/Ion channel
Bioactivity
KPH2f, a dual URAT1/GLUT9 inhibitor, demonstrates safety, oral activity, and efficacy, with inhibitory concentrations (IC50s) of 0.24 μM for URAT1 and 9.37 μM for GLUT9. It exhibits minimal effects on OAT1 and ABCG2, with IC50 values of 32.14 μM and 26.74 μM, respectively [1].
Smiles
[Na+].[O-]C(=O)c1ccccc1CSc1ccncc1Nc1ccc(C#N)c2ccccc12
Molecular Formula
C24H16N3NaO2S
Molecular Weight
433.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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