MELK-8a
Product Specifications
CAS Number
1922153-17-0
Target
Haspin Kinase|||Others|||PDGFR|||MELK
Related Pathways
Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Others
Bioactivity
MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine zipper kinase (MELK), with an IC50 of 2 nM and an IC50 of 0.42 ?M in cellular assays. MELK is crucial in regulating mitosis in cancer cells.
Smiles
O(CC1CCNCC1)C=2C(=CC=NC2)C3=CN(N=C3)C4=CC=C(C=C4)N5CCN(C)CC5
Molecular Formula
C25H32N6O
Molecular Weight
432.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/21A87C2B-CA5E-4A20-B363-9EEED05DF517/T62417
Available Sizes
Curated Selection
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