MELK-8a
Product Specifications
CAS Number
1922153-17-0
Target
Haspin Kinase, Others, PDGFR, MELK
Related Pathways
Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Angiogenesis, Others
Bioactivity
MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine zipper kinase (MELK), with an IC50 of 2 nM and an IC50 of 0.42 μM in cellular assays. MELK is crucial in regulating mitosis in cancer cells.
Smiles
O(CC1CCNCC1)C=2C(=CC=NC2)C3=CN(N=C3)C4=CC=C(C=C4)N5CCN(C)CC5
Molecular Formula
C25H32N6O
Molecular Weight
432.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
040188-PE 200 µL
PLXDC1, CT (PLXDC1, TEM3, TEM7, Plexin domain-containing protein 1, Tumor endothelial marker 3, Tumor endothelial marker 7) (PE) discontinued
Sign In for Pricing
View Details MBS1331162-01 0.02 mg (E-Coli)
Recombinant Haemophilus ducreyi Ribosome-recycling factor (frr)
Sign In for Pricing
View Details MBS1331162-02 0.1 mg (E-Coli)
Recombinant Haemophilus ducreyi Ribosome-recycling factor (frr)
Sign In for Pricing
View Details MBS1331162-03 0.02 mg (Yeast)
Recombinant Haemophilus ducreyi Ribosome-recycling factor (frr)
Sign In for Pricing
View Details