What is the catalog number for FLT3-IN-12?

The catalog number for FLT3-IN-12 is T62412.

What sizes are available for FLT3-IN-12?

FLT3-IN-12 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does FLT3-IN-12 come in?

FLT3-IN-12 is available in 3 different pack sizes.

Is FLT3-IN-12 in stock?

FLT3-IN-12 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FLT3-IN-12?

FLT3-IN-12 is manufactured by Molfinity.

What is the estimated delivery time for FLT3-IN-12?

Estimated delivery time for FLT3-IN-12 is approximately 10 business day(s), depending on your location.

FLT3-IN-12

Product Specifications

CAS Number

2499966-67-3

Target

Others, FLT

Related Pathways

Others, Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

FLT3-IN-12 is a selective, potent, orally active FLT3 kinase inhibitor that acts on FLT3-WT (IC50: 1.48 nM) and FLT3-D835Y (IC50: 2.87 nM) . FLT3-IN-12 is more selective than c-KIT (>1000-fold) . FLT3-IN-12 showed significant anti-AML effects, with an IC50 value of 0.75 nM for MV4-11 cells.