KDM1/CDK1-IN-1
Product Specifications
Target
Others, Caspase, Apoptosis, Histone Demethylase, CDK
Related Pathways
Apoptosis, Proteases/Proteasome, Cell Cycle/Checkpoint, Others, Chromatin/Epigenetic
Bioactivity
KDM1/CDK1-IN-1 (compound 4) is a potent inhibitor of KDM1 (IC50: 0.096 μM) and CDK1 (IC50: 0.078 μM), blocking the cell cycle of HOP-92 cells in the G2/M phase and inducing apoptosis. It is highly cytotoxic to CCRF-CEM cells (IC50: 16.34 μM), HOP-92 cells (IC50: 3.45 μM), and Hep-G2 cells (IC50: 7.79 μM) .
Molecular Formula
C22H17N5O3S
Molecular Weight
431.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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