ALK5-IN-31
Product Specifications
CAS Number
2785430-87-5
Target
Others, TGF-beta/Smad
Related Pathways
Others, Stem Cells
Bioactivity
ALK5-IN-31 is a selective inhibitor of ALK-5 (IC50≤10 nM) and also inhibits TGF-β-induced SMAD signalling.ALK5-IN-31 has the potential to inhibit tumour growth in vivo.ALK5-IN-31 can be used in the study of proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis) .
Smiles
N(C=1C2=C(N=NC1)C(C)=CC=C2)C3=NC(NC4=CC(F)=C(C=C4)N5CCNCC5)=NC=C3
Molecular Formula
C23H23FN8
Molecular Weight
430.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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