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ALK5-IN-31

Product Specifications

CAS Number

2785430-87-5

Target

Others, TGF-beta/Smad

Related Pathways

Others, Stem Cells

Bioactivity

ALK5-IN-31 is a selective inhibitor of ALK-5 (IC50≤10 nM) and also inhibits TGF-β-induced SMAD signalling.ALK5-IN-31 has the potential to inhibit tumour growth in vivo.ALK5-IN-31 can be used in the study of proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis) .

Smiles

N(C=1C2=C(N=NC1)C(C)=CC=C2)C3=NC(NC4=CC(F)=C(C=C4)N5CCNCC5)=NC=C3

Molecular Formula

C23H23FN8

Molecular Weight

430.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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