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RUSKI-201 dihydrochloride

Product Specifications

CAS Number

2320262-09-5

Target

Others, Hedgehog/Smoothened

Related Pathways

Others, GPCR/G Protein, Stem Cells

Bioactivity

RUSKI-201 dihydrochloride is a potent and specific inhibitor of Hedgehog acyltransferase (Hhat) (IC50: 0.20 μM) . It blocks Hh signaling in Shh-overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is a promising Hhat chemical probe for studying Hhat catalytic function.

Smiles

Cl.Cl.CCC(C)CNCC(=O)N1CCc2sccc2C1c1cccc(C)n1

Molecular Formula

C20H29Cl2N3OS

Molecular Weight

430.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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