RUSKI-201 dihydrochloride
Product Specifications
CAS Number
2320262-09-5
Target
Others, Hedgehog/Smoothened
Related Pathways
Others, GPCR/G Protein, Stem Cells
Bioactivity
RUSKI-201 dihydrochloride is a potent and specific inhibitor of Hedgehog acyltransferase (Hhat) (IC50: 0.20 μM) . It blocks Hh signaling in Shh-overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is a promising Hhat chemical probe for studying Hhat catalytic function.
Smiles
Cl.Cl.CCC(C)CNCC(=O)N1CCc2sccc2C1c1cccc(C)n1
Molecular Formula
C20H29Cl2N3OS
Molecular Weight
430.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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