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WZ4002

Product Specifications

CAS Number

1213269-23-8

Target

EGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Purity

0.9812

Bioactivity

WZ4002 is a mutant-selective EGFR inhibitor for EGFR (L858R) and EGFR (T790M) with IC50 of 2 nM/8 nM.

Smiles

O(C)C=1C=C(C=CC1NC=2N=C(OC3=CC(NC(C=C)=O)=CC=C3)C(Cl)=CN2)N4CCN(C)CC4

Molecular Formula

C25H27ClN6O3

Molecular Weight

494.97

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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