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EGFR-IN-40

Product Specifications

CAS Number

1466445-39-5

Target

Tyrosine Kinases, EGFR, Others, BTK

Related Pathways

Tyrosine Kinase/Adaptors, Others, JAK/STAT signaling, Angiogenesis

Bioactivity

EGFR-IN-40 (compound 3z) is a potent inhibitor of BTK (IC50: 1.2 nM), EGFR (IC50: 5.3 nM), and ITK (IC50: 46.1 nM) .

Smiles

O=C1N(C=2C(N=C1C)=CN=C(NC3=CC=C(OC)C=C3)N2)C4=CC(NC(C=C)=O)=CC=C4

Molecular Formula

C23H20N6O3

Molecular Weight

428.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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