EGFR-IN-40

1466445-39-5

Tyrosine Kinases, EGFR, Others, BTK

Tyrosine Kinase/Adaptors, Others, JAK/STAT signaling, Angiogenesis

EGFR-IN-40 (compound 3z) is a potent inhibitor of BTK (IC50: 1.2 nM), EGFR (IC50: 5.3 nM), and ITK (IC50: 46.1 nM) .

O=C1N(C=2C(N=C1C)=CN=C(NC3=CC=C(OC)C=C3)N2)C4=CC(NC(C=C)=O)=CC=C4

C23H20N6O3

428.44

Ice Packs

-20°C