J-1063
Product Specifications
CAS Number
2374772-46-8
Target
Others, TGF-beta/Smad
Related Pathways
Others, Stem Cells
Bioactivity
J-1063 is a selective, orally active and potent inhibitor of ALK5 (IC50: 0.039 μM) . J-1063 inhibits inflammatory infiltration, collagen deposition, hepatocyte necrosis and exhibits anti-fibrotic effects. j-1063 has potential for liver fibrosis studies.
Smiles
C(C(NC1=CC=CC=C1)=O)N2C=C(C(=N2)C=3N=C(C)C=CC3)C4=CC=5C(S4)=CC=NC5
Molecular Formula
C24H19N5OS
Molecular Weight
425.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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