Anti-inflammatory agent 21
Product Specifications
CAS Number
2408836-40-6
Target
Reactive Oxygen Species, NF-κB, Others, NO Synthase
Related Pathways
Immunology/Inflammation, Metabolism, NF-κB, Others
Bioactivity
Anti-inflammatory agent 21 (compound 9o) is a low cytotoxic, orally active anti-inflammatory agent that targets NO (IC50: 0.76 μM) . It accumulates ROS and inhibits the NF-κB/MAPK signaling pathway to exert anti-inflammatory effects, showing beneficial effects on cartilage destruction and inflammatory cell infiltration in a rat model of arthritis.
Smiles
C(O)(C1C=2C(=C(OC)C=C(OC)C2)C(=O)O1)C3=CC=C(OCC4=CC=C(F)C=C4)C=C3
Molecular Formula
C24H21FO6
Molecular Weight
424.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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