18-Deoxyherboxidiene
Product Specifications
CAS Number
1200128-66-0
Target
Others
Related Pathways
Others
Bioactivity
18-Deoxyherboxidiene (RQN-18690A) is a potent inhibitor of angiogenesis that selectively acts on SF3b, a subcomplex of the U2 small nuclear ribonucleoprotein (snRNP) in the spliceosome. It inhibits migration and tube formation in human umbilical vein endothelial cells (HUVEC) without significant cytotoxicity and has potential for cancer research.
Smiles
CCC(OC)C(C)C1OC1(C)CC(C)\C=C\C=C(/C)C1OC(CC(O)=O)CCC1C
Molecular Formula
C25H42O5
Molecular Weight
422.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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