Topo I/COX-2-IN-2
Product Specifications
Target
Others|||Apoptosis|||Reactive Oxygen Species|||COX|||Topoisomerase
Related Pathways
DNA Damage/DNA Repair|||Others|||Neuroscience|||Metabolism|||Apoptosis|||Immunology/Inflammation|||NF-?B
Bioactivity
Topo I/COX-2-IN-2 (Compound W10) is a potent dual inhibitor of Topo I (IC50: 0.90 ?M) and COX-2 (IC50: 2.31 ?M), inducing apoptosis in cancer cells via the mitochondrial pathway.
Molecular Formula
C24H25ClN4O
Molecular Weight
420.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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