Sirt1/2-IN-1
Product Specifications
CAS Number
2402779-21-7
Target
Others, Sirtuin, Microtubule Associated
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair, Cytoskeletal Signaling, Others
Bioactivity
Sirt1/2-IN-1 (Compound 7) is an inhibitor of SIRT1 and SIRT2, with IC50 values of 1.81 μg/mL for SIRT1, 2.10 μg/mL for SIRT2, and 20.5 μg/mL for SIRT3, and exhibits α-microtubulin hyperacetylation activity, demonstrating significant anticancer effects.
Smiles
O=C1N2C(C3=C(C=4C(S3)=CC=C(Cl)C4)N=C2SC1)C5=CC6=C(C=C5)C=CC=C6
Molecular Formula
C22H13ClN2OS2
Molecular Weight
420.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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