Topoisomerase II?-IN-2
Product Specifications
CAS Number
2407521-90-6
Target
Others|||Topoisomerase
Related Pathways
DNA Damage/DNA Repair|||Others
Bioactivity
Topoisomerase II?-IN-2 (compound 5) is a potent inhibitor of the topoisomerase TopoII? and a DNA-binding ligand. It exhibits high anti-proliferative activity in human cancer cell lines, arrests the cell cycle in the G2/M phase, and significantly induces DNA damage.
Smiles
O=C1C=2C(C=3C(OC=4C(N3)=CC=C(C(NCCCC[C@@H](C(O)=O)N)=O)C4)=C1)=CC=CN2
Molecular Formula
C22H20N4O5
Molecular Weight
420.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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