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Topoisomerase II?-IN-2

Product Specifications

CAS Number

2407521-90-6

Target

Others|||Topoisomerase

Related Pathways

DNA Damage/DNA Repair|||Others

Bioactivity

Topoisomerase II?-IN-2 (compound 5) is a potent inhibitor of the topoisomerase TopoII? and a DNA-binding ligand. It exhibits high anti-proliferative activity in human cancer cell lines, arrests the cell cycle in the G2/M phase, and significantly induces DNA damage.

Smiles

O=C1C=2C(C=3C(OC=4C(N3)=CC=C(C(NCCCC[C@@H](C(O)=O)N)=O)C4)=C1)=CC=CN2

Molecular Formula

C22H20N4O5

Molecular Weight

420.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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