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DNA-PK-IN-5

Product Specifications

CAS Number

2719736-43-1

Target

DNA-PK, Others

Related Pathways

Others, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling

Bioactivity

DNA-PK-IN-5 is a potent inhibitor of DNA-PK that inhibits DNA-PKcs activity, significantly reduces tumor DNA repair, and induces apoptosis. It enhances tumor tissue sensitivity to radiotherapy, overcomes drug resistance issues, and improves the inhibition of various solid and haematological tumors.

Smiles

O=C1N(C=2C(N1C)=CN=C(NC3=CC4=C(C=C3C)N=CC=N4)N2)N5CC6OC(C5)CC6

Molecular Formula

C21H22N8O2

Molecular Weight

418.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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