DNA-PK-IN-5
Product Specifications
CAS Number
2719736-43-1
Target
DNA-PK|||Others
Related Pathways
Others|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Bioactivity
DNA-PK-IN-5 is a potent inhibitor of DNA-PK that inhibits DNA-PKcs activity, significantly reduces tumor DNA repair, and induces apoptosis. It enhances tumor tissue sensitivity to radiotherapy, overcomes drug resistance issues, and improves the inhibition of various solid and haematological tumors.
Smiles
O=C1N(C=2C(N1C)=CN=C(NC3=CC4=C(C=C3C)N=CC=N4)N2)N5CC6OC(C5)CC6
Molecular Formula
C21H22N8O2
Molecular Weight
418.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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