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NIC-0102

Product Specifications

CAS Number

2806031-94-5

Target

Others, NOD-like Receptor (NLR), Proteasome

Related Pathways

Others, Ubiquitination, Proteases/Proteasome, Immunology/Inflammation

Bioactivity

NIC-0102 is an orally active proteasome inhibitor (pIC50: 7.55) that specifically inhibits NLRP3 inflammatory vesicle activation.

Smiles

C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)B(O)O)=O)(=O)C2=C(F)C=CC=C2F

Molecular Formula

C21H25BF2N2O4

Molecular Weight

418.24

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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