Selumetinib
Product Specifications
CAS Number
606143-52-6
Target
ERK|||MEK|||Apoptosis
Related Pathways
MAPK|||Apoptosis
Purity
0.999
Bioactivity
Selumetinib (AZD6244) is a MEK1/2 inhibitor that inhibits MEK1 (IC50=14 nM) with potent selectivity and is non-ATP-competitive. Selumetinib has antitumor activity and is used for the treatment of neurofibromatosis type 1 (NF1) .
Smiles
CN1C=NC2=C(F)C(NC3=CC=C(Br)C=C3Cl)=C(C=C12)C(=O)NOCCO
Molecular Formula
C17H15BrClFN4O3
Molecular Weight
457.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6196963-01 0.1 mL
NP (Nucleoside Phosphorylase, FLJ94043, FLJ97288, FLJ97312, MGC117396, MGC125915, MGC125916, PNP, PRO1837, PUNP) (MaxLight 405)
Ask
View Details MBS6196963-02 5x 0.1 mL
NP (Nucleoside Phosphorylase, FLJ94043, FLJ97288, FLJ97312, MGC117396, MGC125915, MGC125916, PNP, PRO1837, PUNP) (MaxLight 405)
Ask
View Details TA810643AM 100 µL
OIP5 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4B1]
Ask
View Details 
248886 50 µL
MRPL13 (Mitochondrial Ribosomal Protein L13, L13, L13A, L13mt, RPL13, RPML13)
Ask
View Details