Selumetinib
Product Specifications
CAS Number
606143-52-6
Target
ERK|||MEK|||Apoptosis
Related Pathways
MAPK|||Apoptosis
Purity
0.999
Bioactivity
Selumetinib (AZD6244) is a MEK1/2 inhibitor that inhibits MEK1 (IC50=14 nM) with potent selectivity and is non-ATP-competitive. Selumetinib has antitumor activity and is used for the treatment of neurofibromatosis type 1 (NF1) .
Smiles
CN1C=NC2=C(F)C(NC3=CC=C(Br)C=C3Cl)=C(C=C12)C(=O)NOCCO
Molecular Formula
C17H15BrClFN4O3
Molecular Weight
457.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[ (2,5-dichlorophenyl) met hyl]-1H-indole-2,3-dione 3- (O-acetyloxime) ) discontinued](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
L1585-25A-01 5 mg
LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[ (2,5-dichlorophenyl) met hyl]-1H-indole-2,3-dione 3- (O-acetyloxime) ) discontinued
Ask
View Details ![LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[ (2,5-dichlorophenyl) met hyl]-1H-indole-2,3-dione 3- (O-acetyloxime) ) discontinued](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
L1585-25A-02 25 mg
LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[ (2,5-dichlorophenyl) met hyl]-1H-indole-2,3-dione 3- (O-acetyloxime) ) discontinued
Ask
View Details 
129390-AP 100 µL
MAP4K5 (Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Kinase Homologous to SPS1/STE20, KHS, MAPK/ERK Kinase Kinase Kinase 5, MEK Kinase Kinase 5, MEKKK 5) (AP) discontinued
Ask
View Details 