Protein deglycase DJ-1 against-1
Product Specifications
CAS Number
724737-74-0
Target
Others, Dopamine Receptor
Related Pathways
Others, Neuroscience, GPCR/G Protein
Purity
0.9723
Bioactivity
Protein deglycase DJ-1 against-1 (compound 23) is able to penetrate the blood-brain barrier (BBB) and bind to the C106 region of the DJ-1 protein, preventing DJ-1 over-oxidation to enhance cellular resistance to oxidative stress, thereby restoring neuronal cellular observed in a neurotoxin MPTP-induced model of Parkinson's disease (PD) death and motor deficits.
Smiles
O=C(NC=1C=CC(=CC1)C=2N=C3C(=CC=CN3C2)C)C4=CC(OC)=C(OC)C(OC)=C4
Molecular Formula
C24H23N3O4
Molecular Weight
417.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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