HDAC8/BRPF1-IN-1
Product Specifications
CAS Number
2484255-85-6
Target
HDAC, Others, Epigenetic Reader Domain
Related Pathways
Others, DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
HDAC8/BRPF1-IN-1 (Compound 23a) is a dual inhibitor targeting human HDAC8 (IC50: 443 nM) and human BRPF1 (Kd: 67 nM), with low in vitro activity against HDAC1 and HDAC6.
Smiles
CN1C=2C(=CC(NS(=O)(=O)C3=C(OC)C=CC(C(NO)=O)=C3)=CC2)C=C(C)C1=O
Molecular Formula
C19H19N3O6S
Molecular Weight
417.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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