KDOAM-25 trihydrochloride
Product Specifications
Target
Others, Histone Demethylase
Related Pathways
Others, Chromatin/Epigenetic
Bioactivity
KDOAM-25 trihydrochloride is a potent and highly selective inhibitor of histone lysine demethylase 5 (KDM5), targeting KDM5A (IC50: 71 nM), KDM5B (IC50: 19 nM), KDM5C (IC50: 69 nM), and KDM5D (IC50: 69 nM) . It enhances overall H3K4 methylation at the transcription start site and hinders the proliferation of multiple myeloma [MM1S cells].
Smiles
O=C(N)C1=CC(CNCC(N(CCN(C)C)CC)=O)=NC=C1.Cl.Cl.Cl
Molecular Formula
C15H28Cl3N5O2
Molecular Weight
416.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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