ALM301
Product Specifications
CAS Number
1313439-71-2
Target
Others, Akt
Related Pathways
Others, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling
Bioactivity
ALM301 is a highly specific, orally active AKT inhibitor that acts on AKT1 (IC50: 0.13 μM), AKT2 (IC50: 0.09 μM) and AKT3 (IC50: 2.75 μM) . ALM301 inhibits AKT phosphorylation in vitro and has a regulatory effect on downstream signalling. ALM301 exhibits inhibitory effects on cancer cell proliferation and tumor growth.
Smiles
CCN1C(=O)COc2nc(-c3ccc(cc3)[C@@]3(N)C[C@H](O)C3)c(cc12)-c1ccccc1
Molecular Formula
C25H25N3O3
Molecular Weight
415.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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