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S-777469

Product Specifications

CAS Number

885496-53-7

Target

Others, Cannabinoid Receptor

Related Pathways

Others, GPCR/G Protein

Bioactivity

S-777469 is a selective, orally active agonist of the cannabinoid type 2 receptor (CB2) (Ki: 36 nM) . s-777469 significantly inhibited compound 48/80-induced scratching behaviour in mice in a dose-dependent manner. s-777469 excites CB2, inhibits pruritic signalling and shows an anti-pruritic effect.

Smiles

CCc1c(C)cc(C(=O)NC2(CCCCC2)C(O)=O)c(=O)n1Cc1ccc(F)cc1

Molecular Formula

C23H27FN2O4

Molecular Weight

414.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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