S-777469
Product Specifications
CAS Number
885496-53-7
Target
Others, Cannabinoid Receptor
Related Pathways
Others, GPCR/G Protein
Bioactivity
S-777469 is a selective, orally active agonist of the cannabinoid type 2 receptor (CB2) (Ki: 36 nM) . s-777469 significantly inhibited compound 48/80-induced scratching behaviour in mice in a dose-dependent manner. s-777469 excites CB2, inhibits pruritic signalling and shows an anti-pruritic effect.
Smiles
CCc1c(C)cc(C(=O)NC2(CCCCC2)C(O)=O)c(=O)n1Cc1ccc(F)cc1
Molecular Formula
C23H27FN2O4
Molecular Weight
414.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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